This paper will quickly describe the preceding conditions and then go on to applying these conditions to five medical research study abstracts that I will describe in more detail while pointing out each study’s potential strengths and weak points.
There are four types of studies you can use in the design of a medical research study, those being a randomized medical trial, case control research, cohort study, and longitudinal study evropski univerzitet. A randomized medical trial study is “a clinical study where volunteer participants with comparable characteristics are randomly assigned to different test groups in order to the efficacy of therapies” (Randomized Clinical Trial, 2011, para. 1). A circumstance control study is epidemiological study used to identify factors that may contribute to a medical illness by comparing those who have the illness or condition of interest (the cases) with those who do not have the disease or current condition of interest (the controls). A cohort study is “a study in which subjects who presently have a certain condition and/or receive a particular treatment are followed as time passes and compared with another team who are not afflicted by the condition under investigation” (What is Cohort Research?, 2011, para. 1). A longitudinal study is a study under patients over a prolonged period of time. Some sources also explain a longitudinal study as one in which the same patients are examined on two or more occasions.
A study can either be retrospective or potential. Retrospective studies look in reverse in time and looks at exposures to suspected risk or protection factors in relation to an outcome that is established at the start of the analysis. In contrast, a possible study looks forward in time and watches for outcomes, like the development of a disease, during the study period and corelates this to other factors such as suspected danger or protection factor(s).
This specific study shows evidence that aspirin use correlates with lowered risks of digestive tract cancer and perhaps several other cancers, including prostate and breast cancer. The examine method examined associations between long-term daily use of adult strength aspirin (325 mg/day) measuring overall tumor incidence and incidence of 10 types of tumor among 69810 men and 76303 women. These men and women, who were relatively elderly, took part in the Cancer Reduction Study.
Since this study is a potential cohort study, it can have several specific strengths and weaknesses. Strengths are that there is the likelihood to study multiple exposures and multiple final results in a single cohort and uncommon exposures can be researched. Major weaknesses are that it is not possible to ascertain causal effects and it is easily prone to selection bias. Likewise, possible cohort studies can be quite expensive to perform.
In summary, reviewing medical research studies can help improve a student’s comprehension of biostatistics and its applications. When reviewing these studies, it is important for students to understand the sort of study used and the potential abilities and failings associated with each study. Following this understanding is achieved, a student will be able to question the validity of medical research that he or she is reading in an objective manner.